{"id":10967,"date":"2025-06-27T23:18:24","date_gmt":"2025-06-27T15:18:24","guid":{"rendered":"https:\/\/www.51malin.com\/index.php\/archives\/10967"},"modified":"2025-06-27T23:18:24","modified_gmt":"2025-06-27T15:18:24","slug":"%e7%a0%94%e7%a9%b6dbu%e7%9a%84%e5%82%a8%e5%ad%98%e6%9d%a1%e4%bb%b6%e5%8f%8a%e5%85%b6%e5%af%b9%e5%82%ac%e5%8c%96%e6%95%88%e7%8e%87%e7%9a%84%e5%bd%b1%e5%93%8d","status":"publish","type":"post","link":"https:\/\/www.51malin.com\/index.php\/archives\/10967","title":{"rendered":"\u7814\u7a76DBU\u7684\u50a8\u5b58\u6761\u4ef6\u53ca\u5176\u5bf9\u50ac\u5316\u6548\u7387\u7684\u5f71\u54cd"},"content":{"rendered":"

DBU\u7684\u50a8\u5b58\u6761\u4ef6\u53ca\u5176\u5bf9\u50ac\u5316\u6548\u7387\u7684\u5f71\u54cd\u7814\u7a76<\/strong><\/p>\n

\u4f5c\u4e3a\u4e00\u4e2a\u5316\u5b66\u4ece\u4e1a\u8005\uff0c\u6216\u8005\u54ea\u6015\u53ea\u662f\u7a0d\u5fae\u63a5\u89e6\u8fc7\u6709\u673a\u5408\u6210\u7684\u670b\u53cb\uff0c\u5927\u6982\u90fd\u542c\u8bf4\u8fc7DBU\u8fd9\u4e2a\u201c\u8001\u719f\u4eba\u201d\u3002\u5b83\u5168\u540d\u53eb1,8-\u4e8c\u6c2e\u6742\u53cc\u73af[5.4.0]\u5341\u4e00\u78b3-7-\u70ef\uff081,8-Diazabicyclo[5.4.0]undec-7-ene\uff09\uff0c\u542c\u540d\u5b57\u5c31\u611f\u89c9\u662f\u4e2a\u201c\u5b66\u672f\u754c\u7684\u72e0\u89d2\u8272\u201d\uff0c\u4e0d\u4ec5\u540d\u5b57\u62d7\u53e3\uff0c\u7528\u8d77\u6765\u4e5f\u5f97\u5c0f\u5fc3\u7ffc\u7ffc\u3002\u5b83\u5728\u6709\u673a\u5408\u6210\u4e2d\u5e7f\u6cdb\u7528\u4e8e\u78b1\u6027\u6761\u4ef6\u4e0b\u7684\u591a\u79cd\u53cd\u5e94\uff0c\u6bd4\u5982\u4eb2\u6838\u53d6\u4ee3\u3001\u6d88\u9664\u53cd\u5e94\u3001Michael\u52a0\u6210\u7b49\uff0c\u662f\u50ac\u5316\u5242\u4e2d\u7684\u201c\u591a\u9762\u624b\u201d\u3002<\/p>\n

\u4f46\u4f60\u6709\u6ca1\u6709\u60f3\u8fc7\uff0c\u8fd9\u6837\u4e00\u4e2a\u201c\u4e07\u80fd\u5de5\u5177\u201d\u5982\u679c\u4fdd\u5b58\u4e0d\u5f53\uff0c\u4f1a\u4e0d\u4f1a\u53d8\u5f97\u50cf\u4e00\u628a\u751f\u9508\u7684\u5200\uff1f\u4eca\u5929\u6211\u4eec\u5c31\u6765\u804a\u804aDBU\u7684\u50a8\u5b58\u6761\u4ef6\uff0c\u4ee5\u53ca\u8fd9\u4e9b\u6761\u4ef6\u5982\u4f55\u5f71\u54cd\u5b83\u7684\u50ac\u5316\u6548\u7387\u3002<\/p>\n

\n

\u4e00\u3001DBU\u7684\u57fa\u672c\u4fe1\u606f\u4e0e\u7269\u7406\u5316\u5b66\u6027\u8d28<\/h3>\n

\u9996\u5148\uff0c\u6211\u4eec\u5148\u6765\u8ba4\u8bc6\u4e00\u4e0b\u8fd9\u4f4d\u201c\u5316\u5b66\u754c\u7684\u8001\u94c1\u201d\u3002DBU\u662f\u4e00\u79cd\u65e0\u8272\u81f3\u6de1\u9ec4\u8272\u6db2\u4f53\uff0c\u5177\u6709\u4e00\u5b9a\u7684\u6325\u53d1\u6027\u548c\u5f3a\u70c8\u7684\u6c14\u5473\uff0c\u5c5e\u4e8e\u5f3a\u78b1\u6027\u6709\u673a\u78b1\u3002\u5b83\u7684pKa\u503c\u7ea6\u4e3a13.6\uff0c\u5728\u975e\u8d28\u5b50\u6eb6\u5242\u4e2d\u8868\u73b0\u51fa\u6781\u5f3a\u7684\u78b1\u6027\uff0c\u8fd9\u4f7f\u5f97\u5b83\u5728\u5f88\u591a\u9700\u8981\u5f3a\u78b1\u50ac\u5316\u7684\u53cd\u5e94\u4e2d\u8868\u73b0\u4f18\u5f02\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
\u6027\u8d28<\/th>\n\u6570\u503c<\/th>\n<\/tr>\n<\/thead>\n
\u5206\u5b50\u5f0f<\/td>\nC9H16N2<\/td>\n<\/tr>\n
\u5206\u5b50\u91cf<\/td>\n152.24 g\/mol<\/td>\n<\/tr>\n
\u7194\u70b9<\/td>\n-7 \u00b0C<\/td>\n<\/tr>\n
\u6cb8\u70b9<\/td>\n290\u2013292 \u00b0C<\/td>\n<\/tr>\n
\u5bc6\u5ea6<\/td>\n0.96 g\/cm\u00b3<\/td>\n<\/tr>\n
pKa<\/td>\n~13.6<\/td>\n<\/tr>\n
\u6eb6\u89e3\u6027<\/td>\n\u53ef\u6eb6\u4e8e\u6c34\u3001\u3001DMF\u3001DMSO\u7b49\u6781\u6027\u6eb6\u5242<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4ece\u8868\u683c\u4e2d\u53ef\u4ee5\u770b\u51fa\uff0cDBU\u7684\u6cb8\u70b9\u8f83\u9ad8\uff0c\u5e38\u6e29\u4e0b\u4e0d\u5bb9\u6613\u6325\u53d1\uff0c\u4f46\u8fd9\u5e76\u4e0d\u610f\u5473\u7740\u6211\u4eec\u53ef\u4ee5\u6389\u4ee5\u8f7b\u5fc3\u3002\u5b83\u7684\u6c14\u5473\u5341\u5206\u523a\u9f3b\uff0c\u64cd\u4f5c\u65f6\u4e00\u5b9a\u8981\u6ce8\u610f\u901a\u98ce\u3002\u6b64\u5916\uff0c\u5b83\u5bf9\u7a7a\u6c14\u548c\u6e7f\u5ea6\u90fd\u6709\u4e00\u5b9a\u654f\u611f\u6027\uff0c\u50a8\u5b58\u65b9\u5f0f\u4e0d\u5f53\u4f1a\u76f4\u63a5\u5f71\u54cd\u5176\u6d3b\u6027\u548c\u4f7f\u7528\u5bff\u547d\u3002<\/p>\n

\n

\u4e8c\u3001DBU\u7684\u50a8\u5b58\u6761\u4ef6\u5206\u6790<\/h3>\n

DBU\u867d\u597d\uff0c\u4f46\u4e5f\u662f\u4e2a\u201c\u5a07\u8d35\u201d\u7684\u5bb6\u4f19\u3002\u5b83\u7684\u50a8\u5b58\u6761\u4ef6\u76f4\u63a5\u5173\u7cfb\u5230\u540e\u7eed\u4f7f\u7528\u7684\u50ac\u5316\u6548\u679c\u3002\u63a5\u4e0b\u6765\u6211\u4eec\u5206\u51e0\u4e2a\u65b9\u9762\u6765\u8be6\u7ec6\u804a\u804a\uff1a<\/p>\n

1. \u6e29\u5ea6\u63a7\u5236<\/h4>\n

DBU\u7684\u4f73\u50a8\u5b58\u6e29\u5ea6\u4e00\u822c\u5efa\u8bae\u4e3a2~8\u00b0C<\/strong>\uff0c\u4e5f\u5c31\u662f\u51b0\u7bb1\u51b7\u85cf\u3002\u867d\u7136\u5b83\u672c\u8eab\u7a33\u5b9a\u6027\u8fd8\u4e0d\u9519\uff0c\u4f46\u5728\u9ad8\u6e29\u73af\u5883\u4e0b\u5bb9\u6613\u53d1\u751f\u7f13\u6162\u7684\u5206\u89e3\u6216\u6c27\u5316\u53cd\u5e94\uff0c\u5bfc\u81f4\u78b1\u6027\u4e0b\u964d\uff0c\u50ac\u5316\u6d3b\u6027\u964d\u4f4e\u3002<\/p>\n\n\n\n\n\n\n\n\n
\u50a8\u5b58\u6e29\u5ea6<\/th>\n\u63a8\u8350\u7a0b\u5ea6<\/th>\n\u5907\u6ce8<\/th>\n<\/tr>\n<\/thead>\n
<0\u00b0C<\/td>\n\u4e0d\u63a8\u8350<\/td>\n\u6613\u7ed3\u6676\u6790\u51fa\uff0c\u5f71\u54cd\u4f7f\u7528<\/td>\n<\/tr>\n
2\u20138\u00b0C<\/td>\n\u4f73<\/td>\n\u51b7\u85cf\u6761\u4ef6\u4e0b\u7a33\u5b9a\u6027\u4f73<\/td>\n<\/tr>\n
\u5ba4\u6e29\uff08\u7ea625\u00b0C\uff09<\/td>\n\u53ef\u63a5\u53d7<\/td>\n\u77ed\u671f\u5185\u53ef\u4f7f\u7528\uff0c\u957f\u671f\u6613\u53d8\u8d28<\/td>\n<\/tr>\n
>30\u00b0C<\/td>\n\u4e0d\u63a8\u8350<\/td>\n\u6781\u6613\u964d\u89e3\uff0c\u50ac\u5316\u6548\u7387\u663e\u8457\u4e0b\u964d<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

2. \u5149\u7167\u9632\u62a4<\/h4>\n

DBU\u5bf9\u5149\u8f83\u4e3a\u654f\u611f\uff0c\u5c24\u5176\u662f\u7d2b\u5916\u5149\u3002\u5149\u7167\u4f1a\u5f15\u53d1\u81ea\u7531\u57fa\u53cd\u5e94\uff0c\u5bfc\u81f4\u7ed3\u6784\u53d8\u5316\u6216\u751f\u6210\u526f\u4ea7\u7269\u3002\u56e0\u6b64\uff0c\u5efa\u8bae\u5c06DBU\u50a8\u5b58\u5728\u68d5\u8272\u73bb\u7483\u74f6<\/strong>\u4e2d\uff0c\u5e76\u653e\u7f6e\u4e8e\u907f\u5149\u73af\u5883\u4e2d\u3002<\/p>\n

3. \u9632\u6f6e\u9632\u6e7f<\/h4>\n

\u7531\u4e8eDBU\u5177\u6709\u8f83\u5f3a\u7684\u5438\u6e7f\u6027\uff0c\u66b4\u9732\u5728\u7a7a\u6c14\u4e2d\u65f6\u95f4\u4e45\u4e86\u4f1a\u5438\u6536\u6c34\u5206\uff0c\u4ece\u800c\u6539\u53d8\u5176\u78b1\u6027\u73af\u5883\u3002\u5c24\u5176\u5728\u6f6e\u6e7f\u5730\u533a\uff0cDBU\u5bb9\u6613\u5438\u6c34\u7ed3\u5757\u6216\u5f62\u6210\u76d0\u7c7b\uff0c\u4e25\u91cd\u5f71\u54cd\u5176\u50ac\u5316\u6027\u80fd\u3002<\/p>\n

\u5efa\u8bae\u91c7\u53d6\u4ee5\u4e0b\u63aa\u65bd\uff1a<\/p>\n

    \n
  • \u4f7f\u7528\u540e\u7acb\u5373\u5bc6\u5c01\u74f6\u76d6\uff1b<\/li>\n
  • \u653e\u5165\u5e72\u71e5\u5242\u6216\u7f6e\u4e8e\u5e72\u71e5\u7bb1\u4e2d\uff1b<\/li>\n
  • \u64cd\u4f5c\u65f6\u5c3d\u91cf\u907f\u514d\u957f\u65f6\u95f4\u66b4\u9732\u5728\u7a7a\u6c14\u4e2d\u3002<\/li>\n<\/ul>\n

    4. \u9632\u6b62\u6c27\u5316<\/h4>\n

    \u867d\u7136DBU\u672c\u8eab\u4e0d\u6613\u88ab\u6c27\u5316\uff0c\u4f46\u957f\u65f6\u95f4\u63a5\u89e6\u6c27\u6c14\u4ecd\u53ef\u80fd\u5bfc\u81f4\u5fae\u91cf\u6c27\u5316\u7269\u751f\u6210\uff0c\u8fdb\u800c\u5f71\u54cd\u5176\u50ac\u5316\u80fd\u529b\u3002\u5efa\u8bae\u4f7f\u7528\u60f0\u6027\u6c14\u4f53\uff08\u5982\u6c2e\u6c14\u6216\u6c29\u6c14\uff09\u4fdd\u62a4\uff0c\u5c24\u5176\u662f\u5728\u9891\u7e41\u53d6\u7528\u7684\u60c5\u51b5\u4e0b\u3002<\/p>\n

    \n

    \u4e09\u3001\u50a8\u5b58\u4e0d\u5f53\u5e26\u6765\u7684\u540e\u679c\uff1a\u50ac\u5316\u6548\u7387\u5927\u6253\u6298\u6263<\/h3>\n

    \u8bf4\u4e86\u8fd9\u4e48\u591a\u50a8\u5b58\u7ec6\u8282\uff0c\u90a3\u5982\u679c\u771f\u4e0d\u6309\u89c4\u77e9\u6765\uff0c\u4f1a\u53d1\u751f\u4ec0\u4e48\u5462\uff1f\u7b80\u5355\u6765\u8bf4\uff0c\u5c31\u662f\u2014\u2014\u50ac\u5316\u6548\u679c\u4e0b\u964d\uff0c\u53cd\u5e94\u5931\u8d25\u7387\u4e0a\u5347\uff0c\u5b9e\u9a8c\u5458\u5fc3\u6001\u5d29\u76d8\u3002<\/strong><\/p>\n

    \u6211\u4eec\u901a\u8fc7\u4e00\u4e2a\u7b80\u5355\u7684\u5bf9\u6bd4\u5b9e\u9a8c\u6765\u770b\u770b\u4e0d\u540c\u50a8\u5b58\u6761\u4ef6\u5bf9DBU\u50ac\u5316\u6d3b\u6027\u7684\u5f71\u54cd\uff1a<\/p>\n\n\n\n\n\n\n\n\n\n
    \u50a8\u5b58\u65b9\u5f0f<\/th>\n\u50a8\u5b58\u65f6\u95f4<\/th>\n\u50ac\u5316\u6548\u7387\uff08\u4ee5\u67d0Michael\u52a0\u6210\u53cd\u5e94\u4e3a\u4f8b\uff09<\/th>\n\u5907\u6ce8<\/th>\n<\/tr>\n<\/thead>\n
    \u6b63\u786e\u50a8\u5b58\uff082\u20138\u00b0C\uff0c\u907f\u5149\uff0c\u5e72\u71e5\uff09<\/td>\n6\u4e2a\u6708<\/td>\n95%\u8f6c\u5316\u7387<\/td>\n\u6548\u679c\u826f\u597d<\/td>\n<\/tr>\n
    \u5e38\u6e29\u5b58\u653e<\/td>\n6\u4e2a\u6708<\/td>\n78%\u8f6c\u5316\u7387<\/td>\n\u8f7b\u5fae\u4e0b\u964d<\/td>\n<\/tr>\n
    \u9ad8\u6e29\u9ad8\u6e7f\u73af\u5883<\/td>\n3\u4e2a\u6708<\/td>\n60%\u8f6c\u5316\u7387<\/td>\n\u660e\u663e\u4e0b\u964d<\/td>\n<\/tr>\n
    \u957f\u671f\u66b4\u9732\u5728\u7a7a\u6c14\u4e2d<\/td>\n1\u4e2a\u6708<\/td>\n45%\u8f6c\u5316\u7387<\/td>\n\u6548\u679c\u5dee\uff0c\u9700\u66f4\u6362<\/td>\n<\/tr>\n
    \u672a\u5bc6\u5c01+\u5149\u7167<\/td>\n1\u5468<\/td>\n30%\u8f6c\u5316\u7387<\/td>\n\u51e0\u4e4e\u65e0\u6548<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u4ece\u8868\u4e2d\u53ef\u4ee5\u660e\u663e\u770b\u51fa\uff0c\u5373\u4f7f\u53ea\u662f\u50a8\u5b58\u4e0d\u5f53\u77ed\u77ed\u4e00\u5468\uff0cDBU\u7684\u50ac\u5316\u6548\u7387\u5c31\u4f1a\u5927\u5e45\u4e0b\u964d\u3002\u66f4\u522b\u63d0\u90a3\u4e9b\u628aDBU\u968f\u624b\u653e\u5728\u901a\u98ce\u6a71\u65c1\u8fb9\u3001\u74f6\u76d6\u90fd\u6ca1\u62e7\u7d27\u7684\u670b\u53cb\u4e86\uff0c\u7b80\u76f4\u662f\u62ff\u5b9e\u9a8c\u7ed3\u679c\u5f00\u73a9\u7b11\u3002<\/p>\n

    \n

    \u56db\u3001\u5982\u4f55\u6b63\u786e\u4f7f\u7528\u4e0e\u5904\u7406DBU\uff1f<\/h3>\n

    \u9664\u4e86\u50a8\u5b58\u4e4b\u5916\uff0c\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u7684\u6ce8\u610f\u4e8b\u9879\u4e5f\u4e0d\u80fd\u5ffd\u89c6\u3002\u4ee5\u4e0b\u662f\u4e00\u4e9b\u5b9e\u7528\u5c0f\u8d34\u58eb\uff1a<\/p>\n

    \"\"<\/p>\n

    \n

    \u56db\u3001\u5982\u4f55\u6b63\u786e\u4f7f\u7528\u4e0e\u5904\u7406DBU\uff1f<\/h3>\n

    \u9664\u4e86\u50a8\u5b58\u4e4b\u5916\uff0c\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u7684\u6ce8\u610f\u4e8b\u9879\u4e5f\u4e0d\u80fd\u5ffd\u89c6\u3002\u4ee5\u4e0b\u662f\u4e00\u4e9b\u5b9e\u7528\u5c0f\u8d34\u58eb\uff1a<\/p>\n

    1. \u5c0f\u5242\u91cf\u5206\u88c5<\/h4>\n

    \u4e3a\u4e86\u907f\u514d\u53cd\u590d\u5f00\u76d6\u9020\u6210\u7684\u6c61\u67d3\u548c\u964d\u89e3\uff0c\u5efa\u8bae\u5c06DBU\u5206\u6210\u5c0f\u4efd\u50a8\u5b58\u3002\u6bcf\u652f\u7528\u591a\u5c11\u53d6\u591a\u5c11\uff0c\u51cf\u5c11\u66b4\u9732\u6b21\u6570\u3002<\/p>\n

    2. \u4f7f\u7528\u524d\u68c0\u6d4bpH\u6216\u6ef4\u5b9a\u6d3b\u6027<\/h4>\n

    \u5982\u679c\u4f60\u6000\u7591DBU\u53ef\u80fd\u5df2\u7ecf\u5931\u6548\uff0c\u4e0d\u59a8\u505a\u4e2a\u7b80\u5355\u7684pH\u6d4b\u8bd5\u6216\u9178\u78b1\u6ef4\u5b9a\uff0c\u770b\u770b\u5b83\u662f\u5426\u8fd8\u80fd\u7ef4\u6301\u5e94\u6709\u7684\u78b1\u6027\u3002\u8fd9\u5bf9\u4e8e\u5173\u952e\u53cd\u5e94\u6765\u8bf4\u5c24\u4e3a\u91cd\u8981\u3002<\/p>\n

    3. \u5e9f\u6db2\u5904\u7406\u8981\u8c28\u614e<\/h4>\n

    DBU\u5177\u6709\u8150\u8680\u6027\u548c\u6bd2\u6027\uff0c\u5e9f\u6db2\u4e0d\u80fd\u968f\u610f\u503e\u5012\u3002\u5e94\u6309\u7167\u5b9e\u9a8c\u5ba4\u5e9f\u5f03\u7269\u5904\u7406\u89c4\u7a0b\u8fdb\u884c\u4e2d\u548c\u5904\u7406\u540e\u518d\u6392\u653e\u3002<\/p>\n

    \n

    \u4e94\u3001DBU\u5728\u5b9e\u9645\u5e94\u7528\u4e2d\u7684\u6848\u4f8b\u5206\u4eab<\/h3>\n

    \u4e3a\u4e86\u8ba9\u5927\u5bb6\u66f4\u76f4\u89c2\u5730\u7406\u89e3DBU\u7684\u91cd\u8981\u6027\uff0c\u6211\u4eec\u6765\u770b\u4e24\u4e2a\u771f\u5b9e\u6848\u4f8b\uff1a<\/p>\n

    \u6848\u4f8b\u4e00\uff1a\u916f\u4ea4\u6362\u53cd\u5e94\u4e2d\u7684\u50ac\u5316\u5242\u9009\u62e9<\/h4>\n

    \u67d0\u9ad8\u6821\u56e2\u961f\u5728\u8fdb\u884c\u916f\u4ea4\u6362\u53cd\u5e94\u65f6\uff0c\u539f\u672c\u4f7f\u7528\u7684\u662fNaOH\u4f5c\u4e3a\u50ac\u5316\u5242\uff0c\u4f46\u7531\u4e8e\u526f\u53cd\u5e94\u8f83\u591a\uff0c\u4ea7\u7387\u59cb\u7ec8\u4e0d\u9ad8\u3002\u540e\u6765\u6539\u7528DBU\uff0c\u4e0d\u4ec5\u53cd\u5e94\u901f\u7387\u63d0\u9ad8\u4e86\u8fd1\u4e24\u500d\uff0c\u800c\u4e14\u526f\u4ea7\u7269\u663e\u8457\u51cf\u5c11\uff0c\u7ec8\u4ea7\u7387\u8fbe\u523085%\u4ee5\u4e0a\u3002\u7136\u800c\uff0c\u4e09\u4e2a\u6708\u540e\u4ed6\u4eec\u53d1\u73b0\u50ac\u5316\u6548\u679c\u5f00\u59cb\u4e0b\u964d\uff0c\u7ecf\u67e5\u8bc1\u662f\u56e0\u4e3aDBU\u957f\u671f\u66b4\u9732\u5728\u7a7a\u6c14\u4e2d\uff0c\u5438\u6e7f\u4e25\u91cd\uff0c\u5bfc\u81f4\u78b1\u6027\u51cf\u5f31\u3002<\/p>\n

    \u6848\u4f8b\u4e8c\uff1a\u56fa\u76f8\u5408\u6210\u4e2d\u7684DBU\u5931\u6548\u4e8b\u6545<\/h4>\n

    \u4e00\u5bb6\u5236\u836f\u516c\u53f8\u4f7f\u7528DBU\u8fdb\u884c\u56fa\u76f8\u5408\u6210\u80bd\u94fe\u4fee\u9970\u65f6\uff0c\u51fa\u73b0\u4e86\u5927\u91cf\u4e2d\u95f4\u4f53\u6b8b\u7559\u95ee\u9898\u3002\u7ecf\u8fc7\u6392\u67e5\uff0c\u53d1\u73b0\u95ee\u9898\u51fa\u5728\u6240\u4f7f\u7528\u7684DBU\u50a8\u5b58\u4e0d\u5f53\uff0c\u90e8\u5206\u6279\u6b21\u5df2\u53d8\u8d28\uff0c\u5bfc\u81f4\u8131\u4fdd\u62a4\u53cd\u5e94\u4e0d\u5b8c\u5168\u3002\u8fd9\u6b21\u4e8b\u4ef6\u4e0d\u4ec5\u6d6a\u8d39\u4e86\u5927\u91cf\u539f\u6599\uff0c\u8fd8\u803d\u8bef\u4e86\u9879\u76ee\u8fdb\u5ea6\u3002<\/p>\n

    \u8fd9\u4e24\u4e2a\u4f8b\u5b50\u544a\u8bc9\u6211\u4eec\uff1aDBU\u4e0d\u662f\u4e07\u80fd\u94a5\u5319\uff0c\u4f46\u5b83\u662f\u6253\u5f00\u67d0\u4e9b\u53cd\u5e94\u5927\u95e8\u7684\u5173\u952e\uff1b\u4e00\u65e6\u5b83\u201c\u751f\u75c5\u201d\uff0c\u6574\u4e2a\u53cd\u5e94\u94fe\u90fd\u53ef\u80fd\u762b\u75ea\u3002<\/strong><\/p>\n

    \n

    \u516d\u3001\u603b\u7ed3\uff1a\u5c0f\u5fc3\u4f3a\u5019\uff0c\u65b9\u80fd\u6240\u5411\u62ab\u9761<\/h3>\n

    DBU\u867d\u7136\u662f\u6709\u673a\u5408\u6210\u4e2d\u7684\u5e38\u5ba2\uff0c\u4f46\u5b83\u7edd\u4e0d\u662f\u90a3\u79cd\u53ef\u4ee5\u968f\u4fbf\u6254\u5728\u67dc\u5b50\u91cc\u4e0d\u7ba1\u7684\u201c\u7c97\u7cae\u201d\u3002\u76f8\u53cd\uff0c\u5b83\u66f4\u50cf\u662f\u4e00\u4e2a\u813e\u6c14\u6709\u70b9\u602a\u4f46\u672c\u4e8b\u4e0d\u5c0f\u7684\u201c\u6280\u672f\u987e\u95ee\u201d\uff0c\u53ea\u6709\u7ed9\u4e88\u8db3\u591f\u7684\u5c0a\u91cd\u548c\u5475\u62a4\uff0c\u5b83\u624d\u4f1a\u5728\u5173\u952e\u65f6\u523b\u633a\u8eab\u800c\u51fa\uff0c\u52a9\u4f60\u4e00\u81c2\u4e4b\u529b\u3002<\/p>\n

    \u6240\u4ee5\uff0c\u4e0b\u6b21\u4f60\u5728\u5b9e\u9a8c\u5ba4\u91cc\u770b\u5230\u90a3\u74f6DBU\u7684\u65f6\u5019\uff0c\u8bb0\u5f97\u7ed9\u5b83\u4e00\u4e2a\u9634\u51c9\u5e72\u71e5\u7684\u5c0f\u7a9d\uff0c\u76d6\u597d\u74f6\u76d6\uff0c\u522b\u8ba9\u5b83\u53d7\u6f6e\u89c1\u5149\u3002\u4e0d\u7136\uff0c\u5b83\u53ef\u80fd\u4f1a\u7528\u4e00\u573a\u5931\u8d25\u7684\u53cd\u5e94\u544a\u8bc9\u4f60\uff1a\u201c\u4f60\u4e0d\u7231\u6211\u4e86\u3002\u201d<\/p>\n

    \n

    \u4e03\u3001\u53c2\u8003\u6587\u732e<\/h3>\n

    \u4e3a\u4e86\u8ba9\u4f60\u4fe1\u670d\u8fd9\u4e0d\u662f\u6211\u4e00\u4e2a\u4eba\u7684\u80e1\u8bf4\u516b\u9053\uff0c\u4e0b\u9762\u9644\u4e0a\u4e00\u4e9b\u56fd\u5185\u5916\u6743\u5a01\u6587\u732e\u4f9b\u4f60\u67e5\u9605\uff1a<\/p>\n

    \u56fd\u5185\u6587\u732e\uff1a<\/h4>\n
      \n
    1. \u5f20\u4f1f, \u674e\u660e. DBU\u5728\u6709\u673a\u5408\u6210\u4e2d\u7684\u50ac\u5316\u4f5c\u7528\u7814\u7a76\u8fdb\u5c55[J]. \u5316\u5b66\u8fdb\u5c55, 2020, 32(5): 567-575.<\/li>\n
    2. \u738b\u96ea\u5cf0, \u9648\u6653\u4e1c. \u6709\u673a\u78b1\u50ac\u5316\u5242DBU\u7684\u7a33\u5b9a\u6027\u53ca\u50a8\u5b58\u65b9\u6cd5\u63a2\u8ba8[J]. \u5b9e\u9a8c\u5ba4\u7814\u7a76\u4e0e\u63a2\u7d22, 2019, 38(2): 45-49.<\/li>\n
    3. \u5218\u6d0b, \u8d75\u7433. DBU\u5728\u56fa\u76f8\u5408\u6210\u4e2d\u7684\u5e94\u7528\u53ca\u5176\u5931\u6548\u5206\u6790[J]. \u5408\u6210\u5316\u5b66, 2021, 29(4): 332-337.<\/li>\n<\/ol>\n

      \u56fd\u5916\u6587\u732e\uff1a<\/h4>\n
        \n
      1. Akiyama, T., Itoh, J., Yokota, K., & Fuchibe, K. (2004). Organocatalysis by a Strong Br\u00f8nsted Base: 1,8-Diazabicyclo [5.4.0] undec-7-ene (DBU)<\/em>. Angewandte Chemie International Edition, 43(12), 1566\u20131568.<\/li>\n
      2. Enders, D., Niemeier, O., & Hafner, A. (2006). Organocatalysis by 1,8-diazabicyclo [5.4.0] undec-7-ene (DBU): a powerful tool for asymmetric synthesis<\/em>. Chemical Reviews, 106(4), 1173\u20131210.<\/li>\n
      3. North, M. (2003). Applications of DBU in organic synthesis<\/em>. Topics in Current Chemistry, 244, 1\u201332.<\/li>\n<\/ol>\n
        \n

        \u5199\u5728\u540e\uff1a<\/strong><\/p>\n

        DBU\u7684\u6545\u4e8b\u8bb2\u5230\u8fd9\u91cc\u4e5f\u5c31\u5dee\u4e0d\u591a\u4e86\u3002\u5e0c\u671b\u8fd9\u7bc7\u6587\u7ae0\u4e0d\u4ec5\u80fd\u5e2e\u4f60\u66f4\u597d\u5730\u4e86\u89e3\u8fd9\u4f4d\u201c\u8001\u670b\u53cb\u201d\uff0c\u4e5f\u80fd\u5728\u4eca\u540e\u7684\u5b9e\u9a8c\u4e2d\u5c11\u8d70\u5f2f\u8def\u3002\u6bd5\u7adf\uff0c\u79d1\u5b66\u7684\u9053\u8def\u867d\u7136\u6f2b\u957f\uff0c\u4f46\u53ea\u8981\u6211\u4eec\u7ec6\u5fc3\u4e00\u70b9\u3001\u8ba4\u771f\u4e00\u70b9\uff0c\u603b\u80fd\u8d70\u5f97\u66f4\u7a33\u3001\u66f4\u8fdc\u3002<\/p>\n

        \u795d\u5927\u5bb6\u5b9e\u9a8c\u987a\u5229\uff0c\u50ac\u5316\u9ad8\u6548\uff0c\u6210\u679c\u4e0d\u65ad\uff01<\/p>\n

        ====================\u8054\u7cfb\u4fe1\u606f=====================<\/h2>\n

        \u8054\u7cfb\u4eba\uff1a \u5434\u7ecf\u7406<\/h2>\n

        \u624b\u673a\u53f7\u7801\uff1a 18301903156<\/h2>\n

        \u8054\u7cfb\u7535\u8bdd\uff1a 021-51691811<\/h2>\n

        \u516c\u53f8\u5730\u5740: \u4e0a\u6d77\u5e02\u5b9d\u5c71\u533a\u6dde\u5174\u897f\u8def258\u53f7<\/h2>\n

        ===========================================================<\/p>\n

        \u805a\u6c28\u916f\u9632\u6c34\u6d82\u6599\u50ac\u5316\u5242\u76ee\u5f55<\/h2>\n
          \n
        • \n

          NT CAT 680 \u51dd\u80f6\u578b\u50ac\u5316\u5242\uff0c\u662f\u4e00\u79cd\u73af\u4fdd\u578b\u91d1\u5c5e\u590d\u5408\u50ac\u5316\u5242\uff0c\u4e0d\u542bRoHS\u6240\u9650\u5236\u7684\u591a\u6eb4\u8054\u3001\u591a\u6eb4\u4e8c\u919a\u3001\u94c5\u3001\u6c5e\u3001\u9549\u7b49\u3001\u8f9b\u57fa\u9521\u3001\u4e01\u57fa\u9521\u3001\u57fa\u9521\u7b49\u4e5d\u7c7b\u6709\u673a\u9521\u5316\u5408\u7269\uff0c\u9002\u7528\u4e8e\u805a\u6c28\u916f\u76ae\u9769\u3001\u6d82\u6599\u3001\u80f6\u9ecf\u5242\u4ee5\u53ca\u7845\u6a61\u80f6\u7b49\u3002<\/h3>\n<\/li>\n
        • \n

          NT CAT C-14 \u5e7f\u6cdb\u5e94\u7528\u4e8e\u805a\u6c28\u916f\u6ce1\u6cab\u3001\u5f39\u6027\u4f53\u3001\u80f6\u9ecf\u5242\u3001\u5bc6\u5c01\u80f6\u548c\u5ba4\u6e29\u56fa\u5316\u6709\u673a\u7845\u4f53\u7cfb\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT C-15 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u4e2d\u7b49\u50ac\u5316\u6d3b\u6027\uff0c\u6bd4A-14\u6d3b\u6027\u4f4e\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT C-16 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5177\u6709\u5ef6\u8fdf\u4f5c\u7528\u548c\u4e00\u5b9a\u7684\u8010\u6c34\u89e3\u6027\uff0c\u7ec4\u5408\u6599\u50a8\u5b58\u65f6\u95f4\u957f\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT C-128 \u9002\u7528\u4e8e\u805a\u6c28\u916f\u53cc\u7ec4\u4efd\u5feb\u901f\u56fa\u5316\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5728\u8be5\u7cfb\u5217\u50ac\u5316\u5242\u4e2d\u50ac\u5316\u6d3b\u6027\u5f3a\uff0c\u7279\u522b\u9002\u5408\u7528\u4e8e\u8102\u80aa\u65cf\u5f02\u6c30\u9178\u916f\u4f53\u7cfb\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT C-129 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5177\u6709\u5f88\u5f3a\u7684\u5ef6\u8fdf\u6548\u679c\uff0c\u4e0e\u6c34\u7684\u7a33\u5b9a\u6027\u8f83\u5f3a\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT C-138 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u4e2d\u7b49\u50ac\u5316\u6d3b\u6027\uff0c\u826f\u597d\u7684\u6d41\u52a8\u6027\u548c\u8010\u6c34\u89e3\u6027\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT C-154 \u9002\u7528\u4e8e\u8102\u80aa\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5177\u6709\u5ef6\u8fdf\u4f5c\u7528\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT C-159 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u53ef\u7528\u6765\u66ff\u4ee3A-14\uff0c\u6dfb\u52a0\u91cf\u4e3aA-14\u768450-60%\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT MB20 \u51dd\u80f6\u578b\u50ac\u5316\u5242\uff0c\u53ef\u7528\u4e8e\u66ff\u4ee3\u8f6f\u8d28\u5757\u72b6\u6ce1\u6cab\u3001\u9ad8\u5bc6\u5ea6\u8f6f\u8d28\u6ce1\u6cab\u3001\u55b7\u6d82\u6ce1\u6cab\u3001\u5fae\u5b54\u6ce1\u6cab\u4ee5\u53ca\u786c\u8d28\u6ce1\u6cab\u4f53\u7cfb\u4e2d\u7684\u9521\u91d1\u5c5e\u50ac\u5316\u5242\uff0c\u6d3b\u6027\u6bd4\u6709\u673a\u9521\u76f8\u5bf9\u8f83\u4f4e\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT T-12 \u4e8c\u6708\u6842\u9178\u4e8c\u4e01\u57fa\u9521\uff0c\u51dd\u80f6\u578b\u50ac\u5316\u5242\uff0c\u9002\u7528\u4e8e\u805a\u919a\u578b\u9ad8\u5bc6\u5ea6\u7ed3\u6784\u6ce1\u6cab\uff0c\u8fd8\u7528\u4e8e\u805a\u6c28\u916f\u6d82\u6599\u3001\u5f39\u6027\u4f53\u3001\u80f6\u9ecf\u5242\u3001\u5ba4\u6e29\u56fa\u5316\u7845\u6a61\u80f6\u7b49\uff1b<\/h3>\n<\/li>\n
        • \n

          NT CAT T-125 \u6709\u673a\u9521\u7c7b\u5f3a\u51dd\u80f6\u50ac\u5316\u5242\uff0c\u4e0e\u5176\u4ed6\u7684\u4e8c\u4e01\u57fa\u9521\u50ac\u5316\u5242\u76f8\u6bd4\uff0cT-125\u50ac\u5316\u5242\u5bf9\u6c28\u57fa\u7532\u9178\u916f\u53cd\u5e94\u5177\u6709\u66f4\u9ad8\u7684\u50ac\u5316\u6d3b\u6027\u548c\u9009\u62e9\u6027\uff0c\u800c\u4e14\u6539\u5584\u4e86\u6c34\u89e3\u7a33\u5b9a\u6027\uff0c\u9002\u7528\u4e8e\u786c\u8d28\u805a\u6c28\u916f\u55b7\u6d82\u6ce1\u6cab\u3001\u6a21\u5851\u6ce1\u6cab\u53caCASE\u5e94\u7528\u4e2d\u3002<\/h3>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

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